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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Issue: January 2023

Volume 8 | Issue 1

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Paper Title: Preparation and Characterization of Oral Fast Dissolving Tablet of Enalapril Maleate using Fenugreek Mucilage as a Superdisintegrant
Authors Name: Kalpak Gajbhiye , Nawaz Hakam , Aman Vyawahare , Swanand Patharkar
Unique Id: IJSDR2006010
Published In: Volume 5 Issue 6, June-2020
Abstract: There are various natural products which can be used for the formulation of various formulations. The current study was carried out by using the fenugreek mucilage as a natural superdisintegrant. The present study was carried out to enhance the drug absorption by dissolving the formulation in the oral cavity itself so that no drug gets metabolized. The prepared tablet was formulated by using fenugreek mucilage as well as sodium starch glycolate in different ratios. The results of pre-compression parameters were found to be satisfactory. The prepared tablet showed the disintegration time in the range of 56-120 sec, average weight was found to be 123-125mg, the average wetting time was found to 19.5 seconds, the thickness was found to be in the range of 2.1-2.9 mm, the hardness was found to be in the range of 2.6-3.5 kg/cm2, the % friability was in the range of 0.48-0.65%, the % drug content was found to be in the range of 99.67-100.22 %, the % drug release was found to be above 90% in 30 minutes. From the study it was concluded that the fast oral dissolving tablet of enalapril maleate was formulated successfully with using natural superdisintegrant.
Keywords: Fast dissolving tablet, Fenugreek mucilage, Antihypertensive drug, Superdisintegrant, Oral dispersible tablet.
Cite Article: "Preparation and Characterization of Oral Fast Dissolving Tablet of Enalapril Maleate using Fenugreek Mucilage as a Superdisintegrant", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 6, page no.64 - 70, June-2020, Available :http://www.ijsdr.org/papers/IJSDR2006010.pdf
Downloads: 000201506
Publication Details: Published Paper ID: IJSDR2006010
Registration ID:191893
Published In: Volume 5 Issue 6, June-2020
DOI (Digital Object Identifier):
Page No: 64 - 70
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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