INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF BISOPROLOL FUMARATE AND TELMISARTAN IN TABLET DOSAGE FORM
A simple, cost effective, reproducible, economical, precise and accurate UV spectroscopic method of Bisoprolol fumarate and Telmisartan in bulk and Besicor-T5 tablet dosage form by using simultaneous equation method. Bisoprolol fumarate and Telmisartan was estimated at their respective wavelengths 223nm and 296nm and at the iso- absorptive wavelength 227nm in methanol as mobile phase. Both Bisoprolol fumarate and Telmisartan follow Beer’s lamberts law over concentration range 1-5µg/ml and 8-40µg/ml, regression of coefficient was found to be r2=0.999 and r2=0.998respectively. The average percentage recovery was found in the range of 99.33 % to 100.74% at three different levels. The method was developed and validated according to ICH Q2 (R2) guidelines. This method can be used for the routine analysis of both the drugs.
"DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF BISOPROLOL FUMARATE AND TELMISARTAN IN TABLET DOSAGE FORM", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 6, page no.58 - 63, June-2020, Available :http://www.ijsdr.org/papers/IJSDR2006009.pdf
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Publication Details:
Published Paper ID: IJSDR2006009
Registration ID:191890
Published In: Volume 5 Issue 6, June-2020
DOI (Digital Object Identifier):
Page No: 58 - 63
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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