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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.15 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Anti TNF- alpha Therapy in Rheumatoid Arthritis: A New Insight |
| Authors Name: | Parsha Shanzana , Tanjia Afrin Chowdhury , Marufatuzzahan |
| Unique Id: | IJSDR1712016 |
| Published In: | Volume 2 Issue 12, December-2017 |
| Abstract: | The development of anti Tumor nacrosis factor alpha (TNF-α) therapies is an alternative to the existing treatments of rheumatoid arthritis (RA). These anti TNF-α therapeutics aim to inhibit the inflammatory activities of TNF-α, which is the major cytokine causing the disease RA. Biologic agents are the newest forms of drugs to treat RA among the disease modifying anti rheumatic drugs (DMARDs). Though, these biologics do not cure the disease, but certainly slow down the progression of the disease with less risk. There are several monoclonal antibody based drugs and fusion proteins which are found to be remarkably successful in this regard. However, comparing the safety concern and immunogenic reactions of these therapeutics this review highlights on further improvements and efficacy of these drugs by subsiding the side effects. |
| Keywords: | Tumor nacrosis factor alpha (TNF-α), anti TNF-α, rheumatoid arthritis (RA), disease modifying anti rheumatic antibody drugs (DMARDS), biologics |
| Cite Article: | "Anti TNF- alpha Therapy in Rheumatoid Arthritis: A New Insight", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.2, Issue 12, page no.110 - 115, December-2017, Available :http://www.ijsdr.org/papers/IJSDR1712016.pdf |
| Downloads: | 000223232 |
| Publication Details: | Published Paper ID: IJSDR1712016 Registration ID:170881 Published In: Volume 2 Issue 12, December-2017 DOI (Digital Object Identifier): Page No: 110 - 115 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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