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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | A REVIEW ON PHARMACOTHERAPY FOR MULTIDRUG RESISTANCE TUBERCULOSIS |
| Authors Name: | P.Pravalika , G.Akhila , M.Himabindhu , K.Hemanth |
| Unique Id: | IJSDR2404185 |
| Published In: | Volume 9 Issue 4, April-2024 |
| Abstract: | Multidrug-resistant tuberculosis (MDR-TB) is a critical global health challenge characterized by bacterial strains of Mycobacterium tuberculosis that have developed resistance to at least two key first-line anti-TB drugs, isoniazid, and rifampicin. The emergence of MDR-TB is primarily attributed to factors such as inadequate treatment regimens, poor patient adherence, and suboptimal healthcare systems. This form of drug resistance not only complicates treatment efforts but also raises concerns about prolonged therapy, increased healthcare costs, and the potential for treatment failure. In more severe cases, extensively drug-resistant tuberculosis (XDR-TB) arises, indicating resistance to additional classes of second-line drugs. Effective management of MDR-TB requires a comprehensive approach, encompassing timely diagnosis through advanced molecular techniques, development of tailored treatment regimens involving second-line drugs, rigorous infection control measures, and innovative research to uncover new therapeutic options. Collaborative efforts between healthcare institutions, governments, and international organizations are imperative to curb the spread of MDR-TB, prevent its further escalation into XDR-TB, and ensure better patient outcomes. These abstract underscores the urgent need for a multifaceted approach to address the challenges posed by multidrug-resistant tuberculosis on a global scale. |
| Keywords: | Multidrug-resistant tuberculosis, first-line anti-TB drugs and second-line drugs |
| Cite Article: | "A REVIEW ON PHARMACOTHERAPY FOR MULTIDRUG RESISTANCE TUBERCULOSIS", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 4, page no.1262 - 1270, April-2024, Available :http://www.ijsdr.org/papers/IJSDR2404185.pdf |
| Downloads: | 000338177 |
| Publication Details: | Published Paper ID: IJSDR2404185 Registration ID:210950 Published In: Volume 9 Issue 4, April-2024 DOI (Digital Object Identifier): Page No: 1262 - 1270 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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